The Hospital Real de Todos os Santos was a major hospital in Lisbon, Portugal. The hospital was built between 1492 and 1504 and was destroyed in the 1755 Lisbon earthquake, along with most of the city.
In 1492, after obtaining papal approval, King John II ordered the building of one of the most important civil and charitative infrastructures in old Lisbon, the Hospital Real de Todos os Santos. The Hospital was finished in 1504, during the reign of King Manuel I. The construction of the Hospital was part of a Royal campaign to centralise the health assistance of the most important cities of the Kingdom into general hospitals. Large hospitals were also founded in Coimbra , Évora and Braga .
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