The Mississippi River is the second-longest river and chief river of the second-largest drainage system on the North American continent, second only to the Hudson Bay drainage system. From its traditional source of Lake Itasca in northern Minnesota, it flows generally south for 2,320 miles to the Mississippi River Delta in the Gulf of Mexico. With its many tributaries, the Mississippi's watershed drains all or parts of 32 U.S. states and two Canadian provinces between the Rocky and Appalachian mountains. The main stem is entirely within the United States; the total drainage basin is 1,151,000 sq mi , of which only about one percent is in Canada. The Mississippi ranks as the fourth-longest river and fifteenth-largest river by discharge in the world. The river either borders or passes through the states of Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana.
Native Americans have lived along the Mississippi River and its tributaries for thousands of years. Most were hunter-gatherers, but some, such as the Mound Builders, formed prolific agricultural and urban civilisations. The arrival of Europeans in the 16th century changed the native way of life as first explorers, then settlers, ventured into the basin in increasing numbers. The river served first as a barrier, forming borders for New Spain, New France, and the early United States, and then as a vital transportation artery and communications link. In the 19th century, during the height of the ideology of manifest destiny, the Mississippi and several western tributaries, most notably the Missouri, formed pathways for the western expansion of the United States.
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