Der var ingen bedøvelser, før Dr. John Snow administrerede ether (dvs. kloroform) til Victoria under fødslerne af Prins Leopold og Prinsesse Beatrice. Leopold blev født den 7. april 1853 på Buckingham Palace i London. Under veerne valgte Dronning Victoria at bruge kloroform og godkendte dermed brugen af bedøvelse ved fødslen, som for nylig var blevet udviklet af Professor James Young Simpson. Dronning Victoria selv kaldte det "det velsignede kloroform" og dets effekt "beroligende, stille og uendeligt herligt". Nogle religiøse ledere og læger var imod dets brug og hævdede, at Gud havde til hensigt, at fødslen skulle være vanskelig: (1 Mosebog 3:16) "Jeg vil gøre dine smerter ved barsel meget svære."
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