Sapientza or Sapienza Σαπιέντζα is a Greek island off the southern coast of the Peloponnese, near the city of Methóni. It is administratively part of the municipality of Pylos-Nestor, in Messenia. The 2011 census reported a population of two inhabitants. Sapientza is the second largest island of the Messenian Oinousses, a small group island which consists of three small islands . Its name is of Italian origin and means wisdom. The Calypso Deep, the deepest point of the Mediterranean Sea at 5,267 metres , is located south-west of Sapientza.



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