The Siege of the Castle of Saint George occurred from 8 November 1500 until 24 December 1500, when following a series of Venetian disasters at the hands of the Turks, the Spanish-Venetian army under Captain Gonzalo Fernández de Córdoba succeeded in capturing the Turkish stronghold of Cephalonia.
Cephalonia, one of the Ionian Islands off the western coast of Greece, had been in the hands of the Italian counts palatine of the Tocco family until 1479, when it was captured by the Ottoman Empire. With the exception of a brief period of Venetian control in 1482–83, the island remained in Ottoman hands until 1500.
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