Mission San Francisco de Asís

Mission San Francisco de Asís, or Mission Dolores, is the oldest surviving structure in San Francisco and the sixth religious settlement established as part of the California chain of missions. The Mission was founded on October 9, 1776, by Francisco Palóu and Co-founder Fray Pedro Combón, both members of the de Anza Expedition, which had been charged with bringing Spanish settlers to Alta California and with evangelizing the local Natives, the Ohlone. Some of the Mission's buildings have been turned into businesses, including a print shop and several saloons.

The settlement was named for St. Francis of Assisi, the founder of the Franciscan Order, but was also commonly known as "Mission Dolores" owing to the presence of a nearby creek named Arroyo de Nuestra Señora de los Dolores, meaning "Our Lady of Sorrows Creek." During the expedition of Juan Bautista de Anza, this site was identified by Pedro Font as the most suitable site for a mission in the San Francisco area.

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