The Big Bayou Canot rail accident was the derailing of an Amtrak train on the CSX Transportation Big Bayou Canot Bridge near Mobile, Alabama, United States, on September 22, 1993. It was caused by displacement of a span and deformation of the rails when a tow of heavy barges collided with the rail bridge eight minutes earlier. 47 people were killed and 103 more were injured. To date, it is both the deadliest train wreck in Amtrak's history and the worst rail disaster in the United States since the 1958 Newark Bay rail accident in which 48 lives were lost.
Immediately prior to the accident, a barge being pushed by the towboat Mauvilla had made a wrong turn on the Mobile River and entered the Big Bayou Canot, an un-navigable channel of water crossed by a CSX Transportation rail bridge.
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