The road from Disentis/Mustér in the canton of Graubünden leads through the Val Medel across the pass to the Blenio valley and Biasca in the canton of Ticino. North of the pass, the road runs along the east shore of Lake Sontga Maria.
Below the Lukmanier Pass, or more precisely between it and Pizzo dell'Uomo, runs the Gotthard Base Tunnel.
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