The Tenth Siege of Gibraltar in 1506 was a minor military action in which the Duke of Medina Sidonia, Juan Alfonso Pérez de Guzmán tried but failed to recover the fortress of Gibraltar from the troops who were holding it in the name of the newly united crowns of Castile and Aragon.
On 3 June 1469 King Henry IV of Castile made a gift of Gibraltar to Enrique de Guzmán, 2nd Duke of Medina Sidonia in return for the effort and expense that his family had put into first capturing this fortress from the Moors and then arranging for settlers and a garrison.
On 30 September 1478 Henry IV's successors,
Ferdinand and Isabella, granted the Duke the title of Marquess of Gibraltar.
Source: Wikipedia.org
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