The 526 Antioch earthquake hit Syria and Antioch in the Byzantine Empire in 526. It struck during late May, probably between 20–29 May, at mid-morning, killing approximately 250,000 people. The earthquake was followed by a fire that destroyed most of the buildings left standing by the earthquake. The maximum intensity in Antioch is estimated to be between VIII and IX on the Mercalli intensity scale.
The site of Antioch lies close to the complex triple junction between the northern end of the Dead Sea Transform, the mainly transform boundary between the African Plate and the Arabian Plate, the southwestern end of the East Anatolian Fault, the mainly transform boundary between the Anatolian Plate and the Arabian Plate, and the northeastern end of the Cyprus Arc, the boundary between the Anatolian and African Plates. The city lies on the Antakya Basin, part of the Amik Basin, filled by Pliocene to recent alluvial sediments. The area has been affected by many large earthquakes during the last 2,000 years.
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