Mississippi County is a county located in the Bootheel of the U.S. state of Missouri, with its eastern border formed by the Mississippi River. As of the 2010 census, the population was 14,358. The largest city and county seat is Charleston. The county was officially organized on February 14, 1845, and was named after the Mississippi River.
Mississippi County is located in what was formerly known as "Tywappity Bottom," a vast floodplain area bordered by the Scott County Hills on the north, St. James Bayou on the south, the Mississippi River on the east, and Little River on the west.
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Address: Missouri, United States
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