The V52 from Paris to Strasbourg already features long developed sections, one of the most remarkable of which crosses Meurthe-et-Moselle. From Toul to Lagarde, a village marking the entrance to Moselle, it offers a getaway of 92 km on a path reserved for cyclists and walkers, guided by the Canal de la Marne au Rhin.

The route can begin in Toul, an old citadel town with a rich military heritage, whose centuries-old ramparts protect a historic center dominated by the Saint-Étienne Cathedral. The itinerary then follows the Moselle Valley towards Nancy, passing at the foot of the citadel village of Villey-le-Sec to arrive in Neuves-Maisons where one can visit the old iron mine. Nancy, which was a flagship city of Art Nouveau, charms with its exceptional heritage, notably a set of 18th-century squares, listed as a UNESCO World Heritage site.

Continuing eastward, the V52 passes very close to the basilica of Saint-Nicolas-de-Port and the salt mine of Varangéville that is still in operation and can be visited. This marks the entrance to the Country of Salt marked by the exploitation of this white gold. Upon arriving in Einville-au-Jard, a detour is necessary to stop in Lunéville. The majesty of the castle and its park in the heart of the city has earned the estate the nickname "Little Lorraine Versailles." Back on the itinerary, the route continues through pastoral landscapes until Lagarde, which marks the entrance to the wetlands of the Lorraine Regional Nature Park.